Darren spent his formative years in Scotland before immigrating to Australia at the age of 12. His career launched at MTV, where he not only hosted but also acted in shows that he helped create.
He gained prominence as the host of the popular game show Minute To Win It in Australia, which later led to him hosting the UK version for ITV. Darren's quick wit and sharp comedic timing made him a natural fit for hosting roles.
He expanded his career internationally with roles such as hosting BBC's Saturday night show The Magicians and NBC's primetime Love in the Wild. Darren also enjoyed hosting stints on The Voice and The Voice Kids in Australia alongside renowned coaches like Ricky Martin, Seal, and Kylie Minogue.
In 2014, Darren joined the cast of Australia's top-rated drama House Husbands, portraying the beloved character 'Alex Larden' and exploring topical issues like gay marriage and surrogacy.
Darren's passion for exploring unique subcultures around the world came to life in National Geographic's Darren McMullen's Outsiders. The show featured him immersing himself in communities like the time-travelling Italians of Damanhur and the alien worshippers known as the Raelians.
After hosting five seasons of The Voice, Darren sought new challenges, finding success as the host of The Big Music Quiz, a comedy panel show on Australia's Channel 7.
Darren's love for NFL football, cultivated since childhood in Scotland, inspired his journey across America to visit all 32 NFL teams, documenting his experiences in the series Football Fanatic, which aired on three American networks.
Returning to Australia from Los Angeles in 2019, Darren starred in Nine's award-winning series SeaChange: Reimagined. He later rejoined The Voice as a co-host alongside Renee Bargh and returned judges Guy Sebastian, Delta Goodrem, Boy George, and Kelly Rowland.
In 2021, Darren landed the lead role in Stan's popular romantic comedy Christmas on the Farm, starring alongside Poppy Montgomery and Hugh Sheridan.
In 2022, Darren showcased his business acumen on The Celebrity Apprentice Australia, finishing as the runner-up while raising over $500,000 for his chosen charity, Feel the Magic.
Following his stint on The Celebrity Apprentice Australia, Darren embarked on a new adventure as the host of Network 10's The Real Love Boat, guiding young singles on their quest for love in the Mediterranean.