Born in Melbourne in 1964 and educated at Christian Brothers College, he began his media career in 1978 as a football statistician with the Herald-Sun newspaper.
In 1982, Eddie joined Channel Ten as a sports journalist and presenter for Eyewitness News where he remained until 1993. In 1997, Eddie and his brother, Walkley Award-winning journalist, Frank McGuire, formed McGuire Media. The company co-produces the hugely successful Triple M radio program The Grill Team.
Eddie is also the author of two bestsellers: Pants: The Darren Milane Story and Footy Show Screamers, and writes a weekly column in Melbourne's Herald Sun. In January 1998, Eddie represented the Australian Republican Movement at the Constitutional Convention in Canberra. He contested the election and was elected with more than 400,000 votes by the people of Victoria.
A passionate and devoted Collingwood football fan since his childhood, Eddie became President of the Club in September 1998. He became the CEO of Channel Nine in 2006. Despite his hectic schedule, he can still find time to help others through the Trevor Barker Foundation.
The foundation honours the memory of the St Kilda star who died after a courageous battle with cancer in 1996. It has raised funds and has bought a home in a Victorian beachside resort for the families of children with cancer. He is a witty and entertaining speaker who is also ideal in an MC role.